Comparing Filitra to the well-known medication Viagra, which is used to treat erectile dysfunction (ED), the active pharmacological element is sildenafil citrate. Sildenafil citrate, a potent selective inhibitor of phosphodiesterase type 5 (PDE5), effectively increases the hemodynamic alterations associated with penile erection by targeting cyclic guanosine monophosphate (cGMP). It works by inhibiting PDE5, which causes smooth muscle relaxation, improves blood flow to the penis during intercourse, and boosts the corpus cavernosum's cGMP levels.